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Publications by Our Staff

Listed in reverse chronological order.

A Multidisciplinary Program By A Team of Experts: Bergein F. Overholt, M.D. John M. Haydek, M.D., Raj I. Narayani, M.D., and Masoud Panjehpour, Ph.D., have 27 Years of Experience in Managing Thousands of Barrett’s Patients.

The Effect of Reactive atypia/Inflammation on the Laser-Induced Fluorescence Diagnosis of Non-dysplastic Barrett’s Esophagus
Panjehpour M, Overholt BF, Vo-Dinh T, Coppola D.
Lasers in Surgery and Medicine. Volume 44, No 5, 390-396, 2012.

Photodynamic therapy in the gastrointestinal tract.
Panjehpour M and Overholt BF.
In: Textbook of Clinical Gastroenterology and Hepatology, second edition, edited by C.J. Hawkey, Jaime Bosch, Joel E. Richter, Guadalupe Garcia-Tsao, Francis K.L. Chan, Chapter 147, page 1111, published by Blackwell Publishing LTD, 2012.

Durability of Radiofrequency Ablation in Barrett’s Esophagus With Dysplasia
Shaheen NJ, Overholt BF, Sampliner RE, Wolfsen HC, Wang KK, Fleischer DE, Sharma VK, Eisen GM, et al.
Gastroenterology. 2011 Aug;141(2):460-8. Epub 2011 May 6

Detection of dysplasia in Barrett’s esophagus with in vivo depth-resolved nuclear morphology measurements
Terry NG, Zhu Y, Rinehart MT, Brown WJ, Gebhart SC, Bright S, Carretta E, Ziefle CG, Panjehpour M, et al.
Gastroenterology. 2011 Jan;140(1):42-50. Epub 2010 Sep 18..

Does Ablative Therapy for Barrett Esophagus Affect the Depth of Subsequent Esophageal Biopsy as Compared With Controls?
Bergein F. Overholt, MD, Patrick J. Dean, MD,Joseph A. Galanko, PhD, and Charles J. Lightdale, MD
Journal of Clinical Gastroenterology,  May 18, 2010

The Case for Endoscopic Treatment of Non-dysplastic and Low-Grade Dysplastic Barrett’s Esophagus
David E. Fleischer, Robert Odze, Bergein F. Overholt, John Carroll, Kenneth J. Chang, Ananya Das, John Goldblum, Daniel Miller, Charles J. Lightdale, Jeffrey Peters, Richard Rothstein, Virender K. Sharma, Daniel Smith, Victor Velanovich, Herbert Wolfsen, George Triadafilopoulos
March 22, 2010, PubMed

Photodynamic therapy for Barrett’s esophagus
Panjehpour M and Overholt BF.
In “Frontiers of Gastrointestinal Research Vol 27, Interventional and Therapeutic Gastrointestinal Endoscopy”, Klaus Monkemuller, C. Mel Wilcox and Miguel Munoz-Navas, editors. Page 128-139, 2010

Radiofrequency Ablation in Barrett’s Esophagus with Dysplasia
Nicholas J. Shaheen, M.D., M.P.H., Prateek Sharma, M.D., Bergein F. Overholt, M.D.
The New England Journal of Medicine 2009

Photodynamic Therapy of Barrett’s Esophagus: Ablation of Barrett’s Mucosa and Reduction in p53 Protein Expression after Treatment.
Panjehpour M, Coppola D, Overholt BF, Vo-Dinh T, Overholt S.
Anticancer Research 2008; 28(1B): 485-489.

Squamous Overgrowth Is Not a Safety Concern for Photodynamic Therapy for Barrett’s Esophagus with High-Grade Dysplasia.
Bronner MP, Overholt BF, Taylor SL, Haggitt RC, et al.
In: Gastroenterology, Volume 136, Issue 1, Pages 56-64, January 2009

Endoscopic ablation of Barrett’s esophagus: a multicenter study with 2.5-year follow-up.
Fleischer DE, Overholt BF, Sharma VK, Reymunde A, et al.
In: Gastrointest Endosc. 2008 Nov;68(5):867-76

Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett’s high-grade dysplasia.
Overholt BF, Wang KK, Burdick JS, Lightdale CJ, et al.
In: Gastrointest Endosc. 2007 Sep;66(3):460-468.

Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett’s esophagus: 1-year follow-up of 100 patients.
Sharma VK, Wang KK, Overholt BF, et al.
In: Gastrointest Endosc. 2007 Feb;65(2):196-9.

Porfimer Sodium Photodynamic Therapy for Management of Barrett’s Esophagus with High Grade Dysplasia
Masoud Panjehpour, Bergein F. Overholt.
In: Laser in Surgery and Medicine, 2006, Volume 38, no 5, pages 390-395.

Photodynamic Therapy for Barrett’s High-Grade Dysplasia
Overholt BF, Panjehpour M, Phan M.
In: Handbook of Gastroenterologic Procedures / senior editor, Douglas A. Drossman; associate editors, Ian S. Grimm, Nicholas J. Shaheen, 4th edition.
Lippincott Williams & Wilkins, 2005.

An Educational Tool for Photodynamic Therapy of Barrett’s Esophagus with High-Grade Dysplasia: From Screening through Follow-up
Phan M, Dyke S, Whittaker MA, Simmerman A, Abrams S, Panjehpour M, Overholt BF.
Gastroenterology Nursing
2005 September/October; 28(5): 413-419

Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett’s esophagus: international, partially blinded, randomized phase III trial.
Overholt BF, Lightdale CJ, Wang KK, Canto MI, Burdick S, Haggitt RC, Bronner MP, Taylor SL, Grace MG, Depot M;
[On behalf of the International Photodynamic Group for High-Grade Dysplasia in Barrett’s Esophagus].
Gastrointestinal Endoscopy
2005 Oct;62(4):488-498

Optimization of light dosimetry for photodynamic therapy of Barrett’s esophagus: efficacy vs. incidence of stricture after treatment.
Panjehpour M, Overholt BF, Phan MN, Haydek JM.
Gastrointestinal Endoscopy
2005 Jan;61(1):13-8

What is the best management strategy for high grade dysplasia in Barrett’s oesophagus? A cost effectiveness analysis.
Shaheen NJ, Inadomi JM, Overholt BF, Sharma P. Gut
2004 Dec;53(12):1736-44

Development of a fluorescence detection system using optical parametric oscillator (OPO) laser excitation for in vivo diagnosis.
Song JM, Jagannathan R, Stokes DL, Kasili PM, Panjehpour M, Phan MN, Overholt BF, DeNovo RC, Pan X, Lee RJ,Vo-Dinh T.
Technol Cancer Res Treat
2003 Dec;2(6):515-23

Photodynamic Therapy for Barrett’s Esophagus with Dysplasia and/or Early Stage Carcinoma: Long Term Results
Overholt BF, Panjehpour M, Halberg B
Gastrointestinal Endoscopy
2003; 58(2):183-8

Therapeutic Applications of Lasers in Gastroenterology
Panjehpour M, Overholt BF.
Biomedical Photonics Handbook, Chapter 46, CRC Press, 2003

Photodynamic Therapy Using Verteporfin (benzoporphyrin derivative monoacid ring A, BPD-MA) and 630 nm Laser Light in Canine Esophagus
Panjehpour M, DeNovo RC, Petersen MG, Overholt BF, Bower R, Rubinchik V, Kelly B.
Lasers in Surgery and Medicine
2002;30(1):26-30

Acid Suppression and Reepithelialization After Ablation of Barrett’s Esophagus
Overholt BF.
Digestive Diseases
2000-2001;18(4):232-9

Evaluating Treatments of Barrett’s Esophagus That Shows High-Grade Dysplasia
Overholt BF.
American Journal of Managed Care
2000 Oct;6(16 Suppl):S903-8

Laser-Induced Fluorescence Spectroscopy for in vivo Diagnosis of Nonmelanoma Skin Cancers
Panjehpour M, Julius CE, Phan MN, Vo-Dinh T, Overholt S.
Lasers in Surgery and Medicine
2002;31(5):367-73

Results of Photodynamic Therapy for Ablation of Dysplasia and Early Cancer in Barrett’s Esophagus and Effect of Oral Steroids on Stricture Formation
Panjehpour M, Overholt BF, Haydek JM, Lee SG.
American Journal of Gastroenterology
2000 Sep;95(9):2177-84

Light Sources and Delivery Devices for Photodynamic Therapy in the Gastrointestinal Tract
Panjehpour M, Overholt BF, Haydek JM.
Gastrointestinal Endoscopy Clinics of North America
2000 Jul;10(3):513-32

Photodynamic Therapy in the Management of Barrett’s Esophagus With Dysplasia
Overholt BF, Panjehpour M.
Journal of Gastrointestinal Surgery
2000 Mar-Apr;4(2):129-30

Results of Photodynamic Therapy in Barrett’s Esophagus: A review
Overholt BF.
Canadian Journal of Gastroenterology
1999 Jun;13(5):393-6

Photodynamic Therapy for Barrett’s Esophagus: Follow-up in 100 Patients
Overholt BF, Panjehpour M, Haydek JM.
Gastrointestinal Endoscopy
1999 Jan;49(1):1-7

Photodynamic Therapy in Barrett’s Esophagus
Overholt BF, Panjehpour M.
Journal of Clinical Laser Medicine & Surgery
1996 Oct;14(5):245-9

Laser-induced Fluorescence for Esophageal Cancer and Dysplasia Diagnosis
Vo-Dinh T, Panjehpour M, Overholt BF.
Annals of the New York Academy of Sciences
1998 Feb 9;838:116-22

Photodynamic Therapy for Barrett’s Esophagus: Cardiac Effects
Overholt BF, Panjehpour M, Ayres M.
Lasers in Surgery and Medicine
1997;21(4):317-20

Photodynamic Therapy for Barrett’s Esophagus
Overholt BF, Panjehpour M.
Gastrointestinal Endoscopy Clinics of North America
1997 Apr;7(2):207-20

Photodynamic Therapy for Barrett’s Esophagus: Clinical Update
Overholt BF, Panjehpour M.
American Journal of Gastroenterology
1996 Sep;91(9):1719-23

Endoscopic Fluorescence Detection of High-Grade Dysplasia in Barrett’s Esophagus
Panjehpour M, Overholt BF, Vo-Dinh T, Haggitt RC, Edwards DH, Buckley FP III.
Gastroenterology
1996 Jul;111(1):93-101

Balloon Photodynamic Therapy of Esophageal Cancer: Effect of Increasing Balloon Size
Overholt BF, Panjehpour M, DeNovo RC, Peterson MG, Jenkins C.
Lasers in Surgery & Medicine
1996;18(3):248-52

Photodynamic Therapy With Porfimer Sodium Versus Thermal Ablation Therapy With Nd: YAG Laser for Palliation of Esophageal Cancer: a Multicenter Randomized Trial
Lightdale CJ, Heier SK, Marcon NE, McCaughan JS Jr, Gerdes H, Overholt BF, Sivak MV Jr, Stiegmann GV, Nava HR.
Gastrointestinal Endoscopy
1995 Dec;42(6):507-12

Photodynamic Therapy in Barrett’s Esophagus: Reduction of Specialized Mucosa, Ablation of Dysplasia, and Treatment of Superficial Esophageal Cancer
Overholt BF, Panjehpour M.
Seminars in Surgical Oncology
1995 Sep-Oct;11(5):372-6

Barrett’s Esophagus: Photodynamic Therapy for Ablation of Dysplasia, Reduction of Specialized Mucosa, and Treatment of Superficial Esophageal Cancer
Overholt BF, Panjehpour M.
Gastrointestinal Endoscopy
1995 Jul;42(1):64-70

Spectroscopic Diagnosis of Esophageal Cancer: New Classification Model, Improved Measurement System
Panjehpour M, Overholt BF, Schmidhammer JL, Farris C, Buckley PF, Vo-Dinh T.
Gastrointestinal Endoscopy
1995 Jun;41(6):577-81

In Vivo Cancer Diagnosis of the Esophagus Using Differential Normalized Fluorescence (DNF) Indices
Vo-Dinh T, Panjehpour M, Overholt BF, Farris C, Buckley FP 3rd, Sneed R.
Lasers in Surgery & Medicine
1995;16(1):41-7

Photodynamic Therapy for Esophageal Cancer Using a 180 Degrees Windowed Esophageal Balloon
Overholt BF, Panjehpour M, DeNovo RC, Petersen MG.
Lasers in Surgery & Medicine
1994;14(1):27-33

Tumor Cell-Enhanced Sensitivity of Vascular Endothelial Cells to Photodynamic Therapy
Yang Z, Lu X, Frazier DL, Panjehpour M, Breider MA.
Lasers in Surgery & Medicine
1994;15(4):342-50

A Centering Balloon for Photodynamic Therapy of Esophageal Cancer Tested in a Canine Model
Overholt BF, DeNovo RC, Panjehpour M, Petersen MG.
Gastrointestinal Endoscopy
1993 Nov-Dec;39(6):782-7

Comparative Study Between Pulsed and Continuous Wave Lasers for Photofrin Photodynamic Therapy
Panjehpour M, Overholt BF, DeNovo RC, Petersen MG, Sneed RE.
Lasers in Surgery & Medicine
1993;13(3):296-304

Photodynamic Therapy for Treatment of Early Adenocarcinoma in Barrett’s Esophagus
Overholt B, Panjehpour M, Tefftellar E, Rose M.
Gastrointestinal Endoscopy
1993 Jan-Feb;39(1):73-6

Quantification of Phthalocyanine Concentration in Rat Tissue Using Laser-Induced Fluorescence Spectroscopy
Panjehpour M, Sneed RE, Frazier DL, Barnhill MA, O’Brien SF, Harb W, Overholt BF.
Lasers in Surgery & Medicine
1993;13(1):23-30

Cytokine Modulation of Endothelial Cell Sensitivity to Photodynamic Therapy
Breider MA, Lu X, Panjehpour M, Frazier DL.
Lasers in Surgery & Medicine
1993;13(3):305-11

Comparative Pharmacokinetics of the Photosensitizer Tin-Etiopurpurin in Dogs and Rats
Frazier DL, Barnhill MA, Vo-Dinh T, Legendre AM, Overholt BF.
Journal of Veterinary Pharmacology and Therapeutics
1992 Sep;15(3):275-81

Laser and Photodynamic Therapy of Esophageal Cancer
Overholt BF.
Seminars in Surgical Oncology
1992 Jul-Aug;8(4):191-203

Centering Balloon to Improve Esophageal Photodynamic Therapy
Panjehpour M, Overholt BF, DeNovo RC, Sneed RE, Petersen MG.
Lasers in Surgery & Medicine
1992;12(6):631-8

Nd:YAG Laser Hyperthermia Treatment of Rat Mammary Adenocarcinoma in Conjunction With Surface Cooling
Panjehpour M, Wilke AV, Frazier DL, Overholt BF.
Lasers in Surgery & Medicine
1991;11(4):356-62

Nd:YAG Laser-Induced Hyperthermia Treatment of Spontaneously Occurring Veterinary Head and Neck Tumors
Panjehpour M, Overholt BF, Frazier DL, Klebanow ER.
Lasers in Surgery & Medicine
1991;11(4):351-5

Nd:YAG Laser-Induced Interstitial Hyperthermia Using a Long Frosted Contact Probe
Panjehpour M, Overholt BF, Milligan AJ, Swaggerty MW, Wilkinson JE, Klebanow ER.
Lasers in Surgery & Medicine
1990;10(1):16-24

Blood Flow Values
Milligan AJ, Panjehpour M.
International Journal of Radiation Oncology, Biology, Physics
1988 May;14(5):1056-7

Laser Treatment of Esophageal Cancer
Overholt BF.
American Journal of Gastroenterology
1985 Sep;80(9):719-20

Canine Normal and Tumor Tissue Estimated Blood Flow During Fractionated Hyperthermia
Milligan AJ, Panjehpour M.
International Journal of Radiation Oncology, Biology, Physics
1985 Sep;11(9):1679-84

Laser Treatment of Upper Gastrointestinal Hemorrhage
Overholt BF.
American Journal of Gastroenterology
1985 Sep;80(9):721-6

The Relationship of Temperature Profiles to Frequency During Interstitial Hyperthermia
Milligan AJ, Panjehpour M.
Association for the Advancement of Medical Instrumentation
1983 Jul-Aug;17(4):303-6